An Information Technology Framework for Predictive, Preventive and Personalised Medicine
An Information Technology Framework for Predictive, Preventive and Personalised Medicine: A Use-Case with Hepatocellular Carcinoma
Springer | Data Mining, 3D Graphics, Gastroenterology & Hepatology, Oncology | March 4 2015 | ISBN-10: 3319121650 | 130 pages | pdf | 4.44 mb
Springer | Data Mining, 3D Graphics, Gastroenterology & Hepatology, Oncology | March 4 2015 | ISBN-10: 3319121650 | 130 pages | pdf | 4.44 mb
This book explores how PPPM, clinical practice, and basic research could be best served by information technology (IT). A use-case was developed for hepatocellular carcinoma (HCC). The subject was approached with four interrelated tasks: (1) review of clinical practices relating to HCC; (2) propose an IT system relating to HCC, including clinical decision support and research needs; (3) determine how a clinical liver cancer center can contribute; and, (4) examine the enhancements and impact that the first three tasks will have on the management of HCC. An IT System for Personalized Medicine (ITS-PM) for HCC will provide the means to identify and determine the relative value of the wide number of variables, including clinical assessment of the patient – functional status, liver function, degree of cirrhosis, and comorbidities; tumor biology, at a molecular, genetic and anatomic level; tumor burden and individual patient response; medical and operative treatments and their outcomes.