"Capsaicin - Sensitive Neural Afferentation and the Gastrointestinal Tract: from Bench to Bedside" ed. by Gyula Mozsik, et al.

This volume is dedicated to the capsaicin, a component of paprika, that has been used in the culinary practice of every day nutritional practice. This agent is known to cause a variety of actions in the body through activating capsaicin-sensitive afferent neurons. This book is for people who are interested in the capsaicin action in body.

This book encompassed review articles written by internationally accepted scientists leading the field of capsaicin research, who highlighted the current state of knowledge on pharmacology, physiology and clinical phathophysiology of capsaicin-sensitive afferent neurons, and discussed directions for future research.

Contents
Preface
1 Discovery and Mechanism of Gastroprotective Action of Capsaicin
2 Pharmacobotanical Analysis and Regulatory Qualification of Capsicum Fruits and Capsicum Extracts — A Survey
3 Allyl Isothiocyanate, a Pungent Ingredient of Wasabi and Mustard Oil, Impairs Gastric Paracellular Barrier in Primary Cultures from the Rat Stomach via TRPAl-Independent Pathway
4 Cooperative Effects of Neuronal Nitric Oxide Synthase and Endothelial Nitric Oxide Synthase on Gastric Hyperemic Response to Intragastric Capsaicin
5 Modulation of Capsaicin-Induced Gastric Protection by Endogenous Prostaglandins through EP2/IP Receptors
6 Mechanism of Capsaicin-Stimulated Gastric HC03-Secretion - Comparison with Mucosal Acidification
7 The Role of Capsaicin-Sensitive Afferent Nerves in Gastric Mucosal Protection Initiated Centrally or Peripherally under Experimental Conditions
8 Stable Gastric PentadecapeptideBPC 157, Somatosensory Neurons and Their Protection and Therapeutic Extensions —A Survey
9 Lafutidine Protects the NSAID-Induced Small Intestinal Lesions Mediated by Capsaicin-Sensitive Afferent Neurons
10 Capsaicin-Sensitive Afferent Nerves and the Human Gastrointestinal Tract
11 Capsaicin is a New Gastrointestinal Mucosal Protecting Drug Candidate in Humans — Pharmaceutical Development and Production Based on Clinical Pharmacology


Prof. Mozsik, a chief editor of this book, is known internationally as an expert in capsaicin pharmacology. Since he has worked for many years as a head of internal medicine, taking care of patients with various GI diseases, he is able to make a correct interpretation of various findings obtained in basic researches to clinical events.