Topical Nail Products and Ungual Drug Delivery
Topical Nail Products and Ungual Drug Delivery by S Narasimha Murthy and Howard I. Maibach
English | 2012 | ISBN: 1439811296 | 282 pages | PDF | 21,5 MB
English | 2012 | ISBN: 1439811296 | 282 pages | PDF | 21,5 MB
Discussing existing techniques, ongoing research, new approaches, and basic concepts in the treatment of nail diseases, Topical Nail Products and Ungual Drug Delivery summarizes the current knowledge and represents a jumping-off point for creating novel techniques of drug delivery across the nail.
A growing area of pharmaceutical research, the search for efficient delivery techniques that can cross the nail barrier has yielded several effective strategies, brought together in this book.
Topics Include
• Nail anatomy, physiology, diseases, and treatment
• Permeability of the nail plate
• Topical nail formulations
• Approaches to enhance ungual and trans-ungual drug delivery
• In vitro and in vivo models to evaluate topical nail formulations
• Nail sampling techniques
• Bioengineering of the nail
• Trans-ungual iontophoresis
• Pharmacokinetics of drugs in the nail apparatus
• Onychopharmacokinetics: proposed model insight
• Photodynamic therapy of nail diseases
• The nail as a surrogate for investigating drug use