In Situ Detection of DNA Damage: Methods and Protocols (Methods in Molecular Biology) by Vladimir V. Didenko
In Situ Detection of DNA Damage: Methods and Protocols (Methods in Molecular Biology) by Vladimir V. Didenko
Humana Press; 2002 edition | April 30, 2002 | English | ISBN: 0896039528 | 279 pages | PDF | 3 MB
Humana Press; 2002 edition | April 30, 2002 | English | ISBN: 0896039528 | 279 pages | PDF | 3 MB
Detection and analysis of DNA damage is of critical importance in a variety of biological disciplines studying apoptosis, cell cycle and cell di- sion, carcinogenesis, tumor growth, embryogenesis and aging, neu- degenerative and heart diseases, anticancer drug development, environmental and radiobiological research, and others. Individual cells within the same tissue or in cell culture may vary in the extent of their DNA damage and, consequently, can display different re- tions to it. These differences between individual cells in the same cell popu- tion are detected using in situ approaches. In situ is a Latin term meaning “on site” or “in place.”