Drug-DNA Interaction Protocols (Methods in Molecular Biology) by Keith R. Fox
Humana Press; 2nd ed. 2010 edition | December 17, 2009 | English | ISBN: 1603274170 | 321 pages | PDF | 16 MB
Humana Press; 2nd ed. 2010 edition | December 17, 2009 | English | ISBN: 1603274170 | 321 pages | PDF | 16 MB
DNA has been known to be the cellular target for many cytotoxic anticancer agents for several decades. The knowledge of its structure in atomic detail and the ease with which DNA fragments (both synthetic oligonucleotides and natural sequences) can be prepared and manipulated has aided the design of compounds that bind to it with improved sel- tivity.