Pui-Yan Kwok, Single Nucleotide Polymorphisms: Methods and Protocols
ISBN: 0896039684 | edition 2002 | PDF | 284 pages | 4 mb
ISBN: 0896039684 | edition 2002 | PDF | 284 pages | 4 mb
Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing.