Nanotechnology and Neuroscience: Nano-electronic, Photonic and Mechanical Neuronal Interfacing by Massimo De Vittorio, Luigi Martiradonna and John Assad
English | 2014 | ISBN: 1489980377 | 318 pages | PDF | 11 MB
English | 2014 | ISBN: 1489980377 | 318 pages | PDF | 11 MB
This book describes the use of modern micro- and nanofabrication technologies to develop improved tools for stimulating and recording electrical activity in neuronal networks. It provides an overview of the different ways in which the “nano-world” can be beneficial for neuroscientists, including improvement of mechanical adhesion of cells on electrodes, tight-sealed extracellular recordings or intracellular approaches with strongly reduced invasiveness, and tools for localized electrical or optical stimulation in optogenetics experiments.
Specific discussion of fabrication strategies is included, to provide a comprehensive guide to develop micro- and nanostructured tools for biological applications. A perspective on integrating these devices with state-of-the-art technologies for large-scale in vitro and in vivo experiments completes the picture of neuronal interfacing with micro- and nanostructures.